1157 – Cell enrichment liquid based cytology in routine screening for the prevention of cervical cancer

Find out about the service or technology in this application and the medical condition it addresses. You can also view the application documents, the deadlines for providing consultation input and the outcome of the application when the MSAC process is complete.

  • Status Complete
  • Type New application
  • Pre-PASC consultation -
  • Pre-MSAC consultation -
  • Outcome Supported

Application details

Reason for application

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Service or technology in this application

Cells are collected from the cervix using a brush, broom or spatula in the same way as they are collected for the conventional pap smear, but the head of the brush or spatula is either rinsed into, or broken off into, a vial of preservative fluid to produce a cell suspension which is sent to a laboratory.

In the direct-to-vial collection method, instead of smearing the cells directly onto a glass slide, cells collected from the cervical scraping are transferred directly to the LBC preservative fluid.

Under LBC at a laboratory, the cell sample is treated to remove obscuring factors, such as blood, mucus and inflammation, so that a thin layer of cervical cells can be placed on a slide for microscopic examination.

Medical condition this application addresses

Women presenting for cervical cytology screening for the identification of abnormal cervical cells.

Meetings to consider this application

  • PASC meeting: 
    • 7 July 2011
  • ESC meeting: 
    • 14 February 2013
  • MSAC meeting: 
    • 5 April 2013
    • 1 August 2013