1189 – Targeted intraoperative radiotherapy (IORT) for early breast cancer

Find out about the service or technology in this application and the medical condition it addresses. You can also view the application documents, the deadlines for providing consultation input and the outcome of the application when the MSAC process is complete.

  • Status Complete
  • Type New application
  • Pre-PASC consultation -
  • Pre-MSAC consultation -
  • Outcome Supported

Application details

Reason for application

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Service or technology in this application

Targeted intraoperative radiotherapy (IORT) is a form of partial breast irradiation which involves giving radiotherapy using the intrabeam device to the tissues surrounding a breast cancer in the operating theatre after surgical removal of the tumour. The rationale of IORT is to accurately target the tissues where there is the highest risk of cancer returning.

Medical condition this application addresses

Early breast cancer. Patients suitable for this modality instead of external beam radiotherapy should meet the following criteria: aged 50 years plus; pathologically documented invasive breast cancer; consideration by the surgeon to be suitable for breast conserving surgery; and no contraindication to breast irradiation.

Application documents

PICO confirmation

Applicant Preferred Protocol Unratified by PASC

Public summary document

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Meetings to consider this application

  • PASC meeting: 16 to 17 April 2014
  • ESC meeting: 8 to 10 October 2014
  • MSAC meeting: 26 to 28 November 2014