1157 - Cell enrichment liquid based cytology in routine screening for the prevention of cervical cancer

Page last updated: 12 October 2016

Application Detail



Description of Medical Service

Cells are collected from the cervix using a brush, broom or spatula in the same way as they are collected for the conventional pap smear, but the head of the brush or spatula is either rinsed into, or broken off into, a vial of preservative fluid to produce a cell suspension which is sent to a laboratory.

In the direct-to-vial collection method, instead of smearing the cells directly onto a glass slide, cells collected from the cervical scraping are transferred directly to the LBC preservative fluid.

Under LBC at a laboratory, the cell sample is treated to remove obscuring factors, such as blood, mucus and inflammation, so that a thin layer of cervical cells can be placed on a slide for microscopic examination.

Description of Medical Condition

Women presenting for cervical cytology screening for the identification of abnormal cervical cells.

Reason for Application


Medical Service Type


Previous Application Number

Not Applicable

Associated Documentation

Application Form


PICO Confirmation

12 – 13 April 2012
Final Decision Analytic Protocol (PDF 856 KB)
Final Decision Analytic Protocol (Word 645 KB)

Assessment Report

15 October 2012
Submission (redacted) (Word 1706 KB)
Submission (redacted) (PDF 2385 KB)

Public Summary Document

PSD April 2013 (redacted) (PDF 164 KB)
PSD April 2013 (redacted) (Word 706 KB)

PSD August 2013 (PDF 71 KB)
PSD August 2013 (Word 72 KB)

Meetings for this Application


7 July 2011


14 February 2013


5 April 2013
1 August 2013