1367 - Gastrointestinal liner ['EndoBarrier'] to treat diabetes and obesity

Page last updated: 25 October 2016

Application Detail

Status

On Hold

Description of Medical Service

EndoBarrier is a duo-denal jejunal bypass sleeve that achieves the metabolic effects of a surgical gastric bypass, with reduced risk. The EndoBarrier prevents nutrient contact with the proximal intestinal mucosa. Bile and pancreatic secretions pass along the outer wall of the impermeable 60cm liner and mix with the chime as it exits distal to the inner in the jejunum. By creating a physical barrier to food absorption, EndoBarrier reduces the uptake of nutrients from the first part of the small bowel and may also have an effect on key metabolic hormones, including intretin. As a result, patients using EndoBarrier may experience substantial clinical benefits in terms of weight loss and glycemic status.

Description of Medical Condition

Type 2 diabetes is a metabolic disorder that is characterised by high blood glucose in the context of insulin resistance and relative insulin deficiency. Long-term complications from high blood sugar can include heart disease, strokes, diabetic retinopathy where eyesight is affected, kidney failure which may require dialysis and poor circulation of limbs leading to amputations. If lifestyle interventions are not successful, patients with type 2 diabetes are generally advised to take oral blood glucose lowering drugs.

Obesity is a medical condition in which excess body fat has accumulated to the extent that it may have an adverse effect on health, leading to reduced life expectancy, and / or increased health problems. Obesity increases the likelihood of various diseases, particularly heart disease, type 2 diabetes, obstructive sleep apnea, certain types of cancer, and osteoarthritis. Clinically severe obesity is a condition generally defined as BMI over 40 or between 35 and 40 where there are other major medical conditions such as high blood pressure and diabetes.

Reason for Application

New MBS item

Medical Service Type

Therapeutic

Previous Application Number

Not Applicable

Associated Documentation


Application Form

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PICO Confirmation

Final Protocol (PDF 422 KB)
Final Protocol (Word 727 KB)

Assessment Report

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Public Summary Document

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Meetings for this Application

PASC

12 - 13 December 2013

ESC

8 - 10 October 2014

MSAC

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