1519 – Tisagenlecleucel (CTL019) for treatment of refractory CD19-positive leukaemia and lymphoma

Find out about the service or technology in this application and the medical condition it addresses. You can also view the application documents, the deadlines for providing consultation input and the outcome of the application when the MSAC process is complete.

  • Status Complete
  • Type New application
  • Pre-PASC consultation -
  • Pre-MSAC consultation -
  • Outcome Supported

Application details

Reason for application

New non-MBS item.

Service or technology in this application

Tisagenlecleucel is an autologous, murine anti-CD19 chimeric antigen receptor T cell (CAR-T) therapeutic process, involving harvesting, modifying, expanding and re-infusing a patient's own immune T-cells, to target and destroy certain cancerous cells.

Type: Hybrid health technology

Medical condition this application addresses

Acute lymphoblastic leukaemia (ALL) is the malignant proliferation of lymphoid progenitor cells in the bone marrow.

Diffuse large B-cell lymphoma (DLBCL) is an aggressive and common subtype of Non-Hodgkin lymphoma (NHL).

Meetings to consider this application

  • PASC meeting: 12 - 13 April 2018
  • ESC meeting: 5 October 2018
  • MSAC meeting: 
    • 22 - 23 November 2018
    • 28 - 29 March 2019
    • 9 April 2019