1653 – Amendment to eligibility criteria for tisagenlecleucel for treatment of relapsed or refractory diffuse large B-cell lymphoma - removal of the requirement for patients to be “CD19-positive”

Page last updated: 16 October 2020

Application Detail

Description of Medical Service

Tisagenlecleucel is an autologous, murine anti-CD19 Chimeric Antigen Receptor T cell therapeutic process, involving harvesting, modifying, expanding and re-infusing a patient's own immune T-cells, to target and destroy certain cancerous cells.

Description of Medical Condition

Diffuse Large B-Cell Lymphoma is an aggressive and common subtype of Non-Hodgkin Lymphoma.

Reason for Application

Request to amend the eligibility criteria to remove the requirement for patients to be “CD19-positive”.

Medical Service Type

Hybrid health technology

Previous Application Number/s

1519
1519.1

Associated Documentation

Public Summary Document

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Meetings for this Application

PASC

Expedited Bypassing PASC

ESC

Expedited Bypassing ESC

MSAC

26-27 November 2020