Description of Medical ServiceCiltacabtagene autoleucel (cilta-cel) is a chimeric antigen receptor T (CAR-T) cell therapy for treatment of patients with multiple myeloma (MM) who are refractory or have failed more than three lines of prior therapy. The therapy involves taking the patient’s own cells from peripheral blood, enriching them for T-cells (a type of white blood cell that is an essential part of the immune system) and genetically modifying them before infusing them back into the patient to treat the MM.
Description of Medical ConditionMultiple Myeloma (MM) is a cancer affecting a type of white blood cell, known as a plasma cell. Plasma cells are found in the bone marrow and make up a part of the immune system. When cancerous, they accumulate to a point where there is not enough space left for normal, healthy blood cells to be produced. MM can cause bone disease, kidney problems, anaemia, increased risk of infection and blood-clotting.
Reason for ApplicationHighly Specialised Therapy- National Health Reform Agreement
Medical Service TypeTherapeutic technology
Previous Application Number/sNot Applicable
Application FormApplication Form (PDF 1422 KB)
Application Form (Word 604 KB)
Consultation SurveyConsultation Survey (PDF 690 KB)
Consultation Survey (Word 72 KB)
PASC consultation closed
MSAC consultation input closed Friday, 10 June 2022.
For further information please refer to PASC, ESC, MSAC Key Dates
For further information on the consultation process please refer to MSAC Consultation Process
PICO ConfirmationPICO Confirmation (PDF 1408 KB)
PICO Confirmation (Word 1348 KB)
Public Summary DocumentPublic Summary Document (PDF 984 KB)
Public Summary Document (Word 373 KB)