1629 – Defensive Antibacterial Coating (DAC) 5ml Kit

Find out about the service or technology in this application and the medical condition it addresses. You can also view the application documents, the deadlines for providing consultation input and the outcome of the application when the MSAC process is complete.

  • Status Complete
  • Type New application
  • Pre-PASC consultation Closed
  • Pre-MSAC consultation Closed
  • Outcome Not supported

Application details

Reason for application

Novel, new product.

Service or technology in this application

DAC is a kit designed for the preparation of a bio-resorbable antibiotic loaded hydrogel, composed of hyaluronan and poly-D,L-lactide copolymer. DAC must be rehydrated using an antibiotic solution. The DAC+antibiotics hydrogel is applied to the surfaces of implants in the orthopaedic and traumatology fields.

Type: Therapeutic

Medical condition this application addresses

The kit is intended to be used for patients at increased risk of periprosthetic infection due to colonisation of an orthopaedic implant during the implant procedure.

Condition 1: Patients with comorbidities known to increase the risk of infection receiving a primary joint implant.

Condition 2: Patients undergoing mega prosthesis implantation or major revision joint implants for indications other than peri-prosthetic infection i.e. total joint revision, tumour removal and reconstruction.

Condition 3: Patients undergoing surgery for peri prosthetic infection with implant replacement.

Condition 4: Patients undergoing open reduction and internal fixation.

Consultation survey and deadlines

  • PASC consultation: Closed
  • MSAC consultation: Closed Friday 7 October 2022

Meetings to consider this application

  • PASC meeting: 13 August 2020
  • ESC meeting: 6 to 7 October 2022
  • MSAC meeting: 24 to 25 November 2022